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Overexpression of sigma-1 receptor inhibits ADAM10 and ADAM17 mediated shedding in vitro
The sigma-1 receptor is a molecular chaperone protein highly enriched in the brain. Recent studies linked it to many diseases, such as drug addition, Alzheimer’s disease, stroke, depression, and even cancer. Sigma-1 receptor is enriched in lipid rafts, which are membrane microdomains essential in si...
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| Publicado no: | Protein Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875409/ https://ncbi.nlm.nih.gov/pubmed/22322890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2006-9 |
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