Chain length-dependent cooperativity in fatty acid binding and oxidation by cytochrome P450(BM3) (CYP102A1)

Fatty acid binding and oxidation kinetics for wild type P450(BM3) (CYP102A1) from Bacillus megaterium have been found to display chain length-dependent homotropic behavior. Laurate and 13-methyl-myristate display Michaelis-Menten behavior while there are slight deviations with myristate at low ionic...

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Publicado en:Protein Cell
Autores principales: Rowlatt, Benjamin, Yorke, Jake A., Strong, Anthony J., Whitehouse, Christopher J. C., Bell, Stephen G., Wong, Luet-Lok
Formato: Artigo
Lenguaje:Inglês
Publicado: Higher Education Press 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875328/
https://ncbi.nlm.nih.gov/pubmed/21904981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1082-6
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