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Regulation of the protein stability of POSH and MLK family

Sequential activation of the JNK pathway components, including Rac1/Cdc42, MLKs (mixed-lineage kinases), MKK4/7 and JNKs, plays a required role in many cell death paradigms. Those components are organized by a scaffold protein, POSH (Plenty of SH3’s), to ensure the effective activation of the JNK pa...

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Détails bibliographiques
Publié dans:Protein Cell
Auteurs principaux: Wang, Chunyan, Tao, Yang, Wang, Yaqing, Xu, Zhiheng
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875233/
https://ncbi.nlm.nih.gov/pubmed/21203929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0111-1
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