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Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA

Integrase plays a critical role in the recombination of viral DNA into the host genome. Therefore, over the past decade, it has been a hot target of drug design in the fight against type 1 human immunodeficiency virus (HIV-1). Bovine immunodeficiency virus (BIV) integrase has the same function as HI...

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Publicado en:Protein Cell
Main Authors: Yao, Xue, Fang, Shasha, Qiao, Wentao, Geng, Yunqi, Shen, Yuequan
Formato: Artigo
Idioma:Inglês
Publicado: Higher Education Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875097/
https://ncbi.nlm.nih.gov/pubmed/21203948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0047-5
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