Differential Requirement for de novo Lipogenesis in Cholangiocarcinoma and Hepatocellular Carcinoma of Mice and Humans

Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most prevalent types of primary liver cancer. These malignancies have limited treatment options resulting in poor patient outcomes. Metabolism reprogramming, including increased de novo lipogenesis, is one of the hallma...

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Udgivet i:Hepatology
Main Authors: Li, Lei, Che, Li, Tharp, Kevin M., Park, Hyo-Min, Pilo, Maria G., Cao, Dan, Cigliano, Antonio, Latte, Gavinella, Xu, Zhong, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Gores, Gregory J., Stahl, Andreas, Calvisi, Diego F., Chen, Xin
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874885/
https://ncbi.nlm.nih.gov/pubmed/26910791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28508
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