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Risk factors for anthracycline-associated cardiotoxicity
PURPOSE: Carbonyl reductase (CBR) catalyzes anthracycline metabolism, and single nucleotide polymorphisms (SNPs) in CBR impact metabolic efficiency. In pediatric patients, homo-zygosity for the major allele (G) in the CBR3 gene was associated with increased risk of anthracycline cardiotoxicity. We h...
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| Publicado no: | Support Care Cancer |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874738/ https://ncbi.nlm.nih.gov/pubmed/26563179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00520-015-3008-y |
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