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Association of osteoprotegerin and bone loss after adjuvant chemotherapy in early-stage breast cancer
PURPOSE: Chemotherapy induced ovarian failure (CIOF) results in rapid bone loss. Receptor Activator of Nuclear Factor Kappa-B (RANK)-RANK ligand (RANK-L) signaling balances bone resorption and formation. Osteoprotegerin (OPG) acts as a decoy receptor for RANK, interrupting osteoclast activation and...
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| Veröffentlicht in: | Mol Cell Endocrinol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4316829/ https://ncbi.nlm.nih.gov/pubmed/25575458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2014.12.028 |
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