FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth

Fibroblast growth factor (FGF) signaling is important for skeletal development; however, cell-specific functions, redundancy and feedback mechanisms regulating bone growth are poorly understood. FGF receptors 1 and 2 (Fgfr1 and Fgfr2) are both expressed in the osteoprogenitor lineage. Double conditi...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Karuppaiah, Kannan, Yu, Kai, Lim, Joohyun, Chen, Jianquan, Smith, Craig, Long, Fanxin, Ornitz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874483/
https://ncbi.nlm.nih.gov/pubmed/27052727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.131722
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