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Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling
Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a direct antagonist of phosphatidylinositol 3 kinase. Pten is a well recognized tumor suppressor and is one of the most commonly mutated genes in human malignancies. More recent studies of development and stem cell behavior have show...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050668/ https://ncbi.nlm.nih.gov/pubmed/21385768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058016 |
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