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Overexpression of a Cytosolic Pyrophosphatase (TgPPase) Reveals a Regulatory Role of Pyrophosphate in Glycolysis for Toxoplasma gondii

Pyrophosphate (PP(i)) is a critical element of cellular metabolism as both an energy donor and as an allosteric regulator of several metabolic pathways. The apicomplexan parasite, Toxoplasma gondii, uses PP(i) in place of ATP as an energy donor in at least two reactions: the glycolytic PP(i)-depende...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Pace, Douglas A., Fang, Jianmin, Cintrón, Roxana, Docampo, Melissa D., Moreno, Silvia N. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874478/
https://ncbi.nlm.nih.gov/pubmed/21831041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110641
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