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Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting

Acute myelogenous leukemia is propagated by a subpopulation of leukemia stem cells (LSCs). In this article, we review both the intrinsic and extrinsic components that are known to influence the survival of human LSCs. The intrinsic factors encompass regulators of cell cycle and prosurvival pathways...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Konopleva, Marina Y., Jordan, Craig T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874213/
https://ncbi.nlm.nih.gov/pubmed/21220598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.0904
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