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Impact of Young Age on Treatment Efficacy and Safety in Advanced Colorectal Cancer: A Pooled Analysis of Patients From Nine First-Line Phase III Chemotherapy Trials

PURPOSE: Colorectal cancer predominantly occurs in the elderly, but approximately 5% of patients are 50 years old or younger. We sought to determine whether young age is prognostic, or whether it influences efficacy/toxicity of chemotherapy, in patients with advanced disease. METHODS: We analyzed in...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Blanke, Charles D., Bot, Brian M., Thomas, David M., Bleyer, Archie, Kohne, Claus-Henning, Seymour, Matthew T., de Gramont, Aimery, Goldberg, Richard M., Sargent, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874194/
https://ncbi.nlm.nih.gov/pubmed/21646604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.5281
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