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Inference of kinship using spatial distributions of SNPs for genome-wide association studies

BACKGROUND: Genome-wide association studies (GWASs) are powerful in identifying genetic loci which cause complex traits of common diseases. However, it is well known that inappropriately accounting for pedigree or population structure leads to spurious associations. GWASs have often encountered incr...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Lee, Hyokyeong, Chen, Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873983/
https://ncbi.nlm.nih.gov/pubmed/27206321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2696-0
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