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Inference of kinship using spatial distributions of SNPs for genome-wide association studies

BACKGROUND: Genome-wide association studies (GWASs) are powerful in identifying genetic loci which cause complex traits of common diseases. However, it is well known that inappropriately accounting for pedigree or population structure leads to spurious associations. GWASs have often encountered incr...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Lee, Hyokyeong, Chen, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873983/
https://ncbi.nlm.nih.gov/pubmed/27206321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2696-0
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