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Imaging Tumor Vascularity and Response to Anti-Angiogenic Therapy Using Gaussia Luciferase

We developed a novel approach to assess tumor vascularity using recombinant Gaussia luciferase (rGluc) protein and bioluminescence imaging. Upon intravenous injection of rGluc followed by its substrate coelenterazine, non-invasive visualization of tumor vascularity by bioluminescence imaging was pos...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Kantar, Rami S., Lashgari, Ghazal, Tabet, Elie I., Lewandrowski, Grant K., Carvalho, Litia A., Tannous, Bakhos A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873808/
https://ncbi.nlm.nih.gov/pubmed/27198044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26353
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