In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone

RATIONALE: Nicotine, a dominant alkaloid found in tobacco, is responsible for physical dependence, as well as addiction to cigarette smoking; consequently, smoking cessation is a very difficult process. Hepatic cytochrome P-450 2A6 (CYP2A6) is involved in the 70–80 % of the initial metabolism of nic...

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Bibliografiske detaljer
Udgivet i:Psychopharmacology (Berl)
Main Authors: Budzynska, Barbara, Skalicka-Wozniak, Krystyna, Kruk-Slomka, Marta, Wydrzynska-Kuzma, Malgorzata, Biala, Grazyna
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873531/
https://ncbi.nlm.nih.gov/pubmed/27080866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4279-9
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