CSF1 overexpression promotes high-grade glioma formation without impacting the polarization status of glioma-associated microglia and macrophages

Current therapies for high-grade gliomas extend survival only modestly. The glioma microenvironment, including glioma-associated microglia/macrophages (GAMs), is a potential therapeutic target. The microglia/macrophage cytokine CSF1 and its receptor CSF1R are overexpressed in human high-grade glioma...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: De, Ishani, Steffen, Megan D., Clark, Paul A., Patros, Clayton J., Sokn, Emily, Bishop, Stephanie M., Litscher, Suzanne, Maklakova, Vilena I., Kuo, John S., Rodriguez, Fausto J., Collier, Lara S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873447/
https://ncbi.nlm.nih.gov/pubmed/27013192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2386
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