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Polysome profiling links translational control to the radioresponse of glioblastoma stem-like cells

Changes in polysome-bound mRNA (translatome) are correlated closely with changes in the proteome in cells. Therefore, to better understand the processes mediating the response of glioblastoma (GBM) to ionizing radiation (IR), we used polysome profiling to define the IR-induced translatomes of a set...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Wahba, Amy, Rath, Barbara H., Bisht, Kheem, Camphausen, Kevin, Tofilon, Philip J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873349/
https://ncbi.nlm.nih.gov/pubmed/27005284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3050
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