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Neurosteroids and epileptogenesis in the pilocarpine model: Evidence for a relationship between P450scc induction and length of the latent period

PURPOSE: Cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc) catalyzes the initial step in the biosynthesis of neurosteroids within the brain. We sought to determine which cells express P450cc and whether neurosteroids play a role in the regulation of epileptogenesis following pilocarpi...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Biagini, Giuseppe, Longo, Daniela, Baldelli, Enrica, Zoli, Michele, Rogawski, Michael A., Bertazzoni, Giuliano, Avoli, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873280/
https://ncbi.nlm.nih.gov/pubmed/19125849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2008.01971.x
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