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Neurosteroidal modulation of in vitro epileptiform activity is enhanced in pilocarpine-treated epileptic rats

We employed field potential recordings in brain slices obtained from pilocarpine-treated epileptic (4–5 weeks following a pilocarpine-induced status epilepticus) and age-matched, non-epileptic control (NEC) rats to establish the effects of the neurosteroid allotetrahydrodeoxycorticosterone (THDOC) o...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Shiri, Zahra, Herrington, Rochelle, Lévesque, Maxime, Avoli, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880464/
https://ncbi.nlm.nih.gov/pubmed/25814046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.03.020
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