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CXCR6-CXCL16 axis promotes prostate cancer by mediating cytoskeleton rearrangement via Ezrin activation and α(v)β(3) integrin clustering

Cytoskeletal rearrangement is required for migration and invasion, which are the key steps of cancer metastasis. Ezrin and integrin co-ordinate these processes by regulating cellular adhesion and cytoskeletal polymerization-depolymerization. It is also well established that chemokine-chemokine recep...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Singh, Rajesh, Kapur, Neeraj, Mir, Hina, Singh, Nalinaksha, Lillard, James W., Singh, Shailesh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872790/
https://ncbi.nlm.nih.gov/pubmed/26799186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6944
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