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CXCR2 signaling regulates KRAS((G12D))-induced autocrine growth of pancreatic cancer
Pharmacological inhibition of RAS, the master regulator of pancreatic ductal adenocarcinoma (PDAC), continues to be a challenge. Mutations in various isoforms of RAS gene, including KRAS are known to upregulate CXC chemokines; however, their precise role in KRAS-driven pancreatic cancer remains uncl...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872785/ https://ncbi.nlm.nih.gov/pubmed/26771140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6906 |
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