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miRNA-29a as a tumor suppressor mediates PRIMA-1(Met)-induced anti-myeloma activity by targeting c-Myc
The proto-oncogene c-Myc plays substantial role in multiple myeloma (MM) pathogenesis and is considered a potential drug target. Here we provide evidence of a novel mechanism for PRIMA-1(Met), a small molecule with anti-tumor activity in phase I/II clinical trial, showing that PRIMA-1(Met) induces a...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872775/ https://ncbi.nlm.nih.gov/pubmed/26771839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6880 |
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