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Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia

Myelodysplastic syndromes (MDS) represent a broad spectrum of diseases characterized by their clinical manifestation as one or more cytopenias, or a reduction in circulating blood cells. MDS is predominantly a disease of the elderly, with a median age in the UK of around 75. Approximately one third...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liberante, Fabio Giuseppe, Pouryahya, Tara, McMullin, Mary-Frances, Zhang, Shu-Dong, Mills, Kenneth Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872736/
https://ncbi.nlm.nih.gov/pubmed/26735888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6773
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