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Coupling Gd-DTPA with a bispecific, recombinant protein anti-EGFR-iRGD complex improves tumor targeting in MRI

Recombinant anti-epidermal growth factor receptor-internalizing arginine-glycine-aspartic acid (anti-EGFR single-domain antibody fused with iRGD peptide) protein efficiently targets the EGFR extracellular domain and integrin αvβ/β5, and shows a high penetration into cells. Thus, this protein may imp...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: XIN, XIAOYAN, SHA, HUIZI, SHEN, JINGTAO, ZHANG, BING, ZHU, BIN, LIU, BAORUI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872280/
https://ncbi.nlm.nih.gov/pubmed/27035336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4712
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