iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer

Poor infiltration of activated lymphocytes into tumors represents a fundamental factor limiting the therapeutic effect of adoptive cell immunotherapy. A tumor-penetrating peptide, iRGD, has been widely used to deliver drugs into tumor tissues. In this study, we demonstrate for the first time that iR...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ding, Naiqing, Zou, Zhengyun, Sha, Huizi, Su, Shu, Qian, Hanqing, Meng, Fanyan, Chen, Fangjun, Du, Shiyao, Zhou, Shujuan, Chen, Hong, Zhang, Lianru, Yang, Ju, Wei, Jia, Liu, Baorui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430780/
https://ncbi.nlm.nih.gov/pubmed/30902997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09296-6
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