Overcoming resistance to first/second generation epidermal growth factor receptor tyrosine kinase inhibitors and ALK inhibitors in oncogene-addicted advanced non-small cell lung cancer

Epidermal growth factor receptor (EGFR) activating mutations and anaplastic lymphoma kinase (ALK) gene rearrangement in advanced non-small cell lung cancer (NSCLC) represent the two oncogenic events with an impact on current clinical practice. EGFR tyrosine kinase inhibitors (TKIs) and crizotinib ar...

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Bibliographic Details
Published in:Ther Adv Med Oncol
Main Authors: Romanidou, Ourania, Landi, Lorenza, Cappuzzo, Federico, Califano, Raffaele
Format: Artigo
Language:Inglês
Published: SAGE Publications 2016
Subjects:
Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872250/
https://ncbi.nlm.nih.gov/pubmed/27239236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834016631531
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