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Endocytosis of indium-tin-oxide nanoparticles by macrophages provokes pyroptosis requiring NLRP3-ASC-Caspase1 axis that can be prevented by mesenchymal stem cells

The biological effects of indium-tin-oxide (ITO) are of considerable importance because workers exposed to indium compounds have been diagnosed with interstitial lung disease or pulmonary alveolar proteinosis; however, the pathophysiology of these diseases is undefined. Here, mice intraperitoneally...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Naji, Abderrahim, Muzembo, Basilua André, Yagyu, Ken-ichi, Baba, Nobuyasu, Deschaseaux, Frédéric, Sensebé, Luc, Suganuma, Narufumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872131/
https://ncbi.nlm.nih.gov/pubmed/27194621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26162
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