The mutation spectrum in genomic late replication domains shapes mammalian GC content

Genome sequence compositions and epigenetic organizations are correlated extensively across multiple length scales. Replication dynamics, in particular, is highly correlated with GC content. We combine genome-wide time of replication (ToR) data, topological domains maps and detailed functional epige...

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Bibliografiske detaljer
Udgivet i:	Nucleic Acids Res
Main Authors:	Kenigsberg, Ephraim, Yehuda, Yishai, Marjavaara, Lisette, Keszthelyi, Andrea, Chabes, Andrei, Tanay, Amos, Simon, Itamar
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2016
Fag:	Genomics
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4872117/ https://ncbi.nlm.nih.gov/pubmed/27085808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw268
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The mutation spectrum in genomic late replication domains shapes mammalian GC content

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