The mutation spectrum in genomic late replication domains shapes mammalian GC content

Genome sequence compositions and epigenetic organizations are correlated extensively across multiple length scales. Replication dynamics, in particular, is highly correlated with GC content. We combine genome-wide time of replication (ToR) data, topological domains maps and detailed functional epige...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Kenigsberg, Ephraim, Yehuda, Yishai, Marjavaara, Lisette, Keszthelyi, Andrea, Chabes, Andrei, Tanay, Amos, Simon, Itamar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Genomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872117/
https://ncbi.nlm.nih.gov/pubmed/27085808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw268
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