Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

The chemically most complex modification in eukaryotic rRNA is the conserved hypermodified nucleotide N1-methyl-N3-aminocarboxypropyl-pseudouridine (m(1)acp(3)Ψ) located next to the P-site tRNA on the small subunit 18S rRNA. While S-adenosylmethionine was identified as the source of the aminocarboxy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Meyer, Britta, Wurm, Jan Philip, Sharma, Sunny, Immer, Carina, Pogoryelov, Denys, Kötter, Peter, Lafontaine, Denis L. J., Wöhnert, Jens, Entian, Karl-Dieter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Nucleic Acid Enzymes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872110/
https://ncbi.nlm.nih.gov/pubmed/27084949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw244
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