Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

The chemically most complex modification in eukaryotic rRNA is the conserved hypermodified nucleotide N1-methyl-N3-aminocarboxypropyl-pseudouridine (m(1)acp(3)Ψ) located next to the P-site tRNA on the small subunit 18S rRNA. While S-adenosylmethionine was identified as the source of the aminocarboxy...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Meyer, Britta, Wurm, Jan Philip, Sharma, Sunny, Immer, Carina, Pogoryelov, Denys, Kötter, Peter, Lafontaine, Denis L. J., Wöhnert, Jens, Entian, Karl-Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872110/
https://ncbi.nlm.nih.gov/pubmed/27084949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw244
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