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Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

The function of RNA is subtly modulated by post-transcriptional modifications. Here, we report an important crosstalk in the covalent modification of two classes of RNAs. We demonstrate that yeast Kre33 and human NAT10 are RNA cytosine acetyltransferases with, surprisingly, specificity toward both 1...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Sharma, Sunny, Langhendries, Jean-Louis, Watzinger, Peter, Kötter, Peter, Entian, Karl-Dieter, Lafontaine, Denis L.J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344512/
https://ncbi.nlm.nih.gov/pubmed/25653167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv075
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