Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

The function of RNA is subtly modulated by post-transcriptional modifications. Here, we report an important crosstalk in the covalent modification of two classes of RNAs. We demonstrate that yeast Kre33 and human NAT10 are RNA cytosine acetyltransferases with, surprisingly, specificity toward both 1...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Sharma, Sunny, Langhendries, Jean-Louis, Watzinger, Peter, Kötter, Peter, Entian, Karl-Dieter, Lafontaine, Denis L.J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344512/
https://ncbi.nlm.nih.gov/pubmed/25653167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv075
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