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An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation
During translation initiation, eukaryotic initiation factor 2 (eIF2) delivers the Met-tRNA to the 40S ribosomal subunit to locate the initiation codon (AUG(i)) of mRNA during the scanning process. Stress-induced eIF2 phosphorylation leads to a general blockade of translation initiation and represent...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872096/ https://ncbi.nlm.nih.gov/pubmed/26984530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw172 |
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