Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast

In budding yeast, Set2 catalyzes di- and trimethylation of H3K36 (H3K36me2 and H3K36me3) via an interaction between its Set2–Rpb1 interaction (SRI) domain and C-terminal repeats of RNA polymerase II (Pol2) phosphorylated at Ser(2) and Ser(5) (CTD-S2,5-P). H3K36me2 is sufficient for recruitment of th...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Suzuki, Shota, Kato, Hiroaki, Suzuki, Yutaka, Chikashige, Yuji, Hiraoka, Yasushi, Kimura, Hiroshi, Nagao, Koji, Obuse, Chikashi, Takahata, Shinya, Murakami, Yota
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872076/
https://ncbi.nlm.nih.gov/pubmed/26792892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw008
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