Ser7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAi

Some long noncoding RNAs (ncRNAs) transcribed by RNA polymerase II (RNAPII) are retained on chromatin, where they regulate RNAi and chromatin structure. The molecular basis of this retention remains unknown. We show that in fission yeast serine 7 (Ser7) of the C-terminal domain (CTD) of RNAPII is re...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kajitani, Takuya, Kato, Hiroaki, Chikashige, Yuji, Tsutsumi, Chihiro, Hiraoka, Yasushi, Kimura, Hiroshi, Ohkawa, Yasuyuki, Obuse, Chikashi, Hermand, Damien, Murakami, Yota
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748204/
https://ncbi.nlm.nih.gov/pubmed/29237752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714579115
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