Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence

Identifying prostate cancer-driving transcription factors (TFs) in addition to the androgen receptor promises to improve our ability to effectively diagnose and treat this disease. We employed an integrative genomics analysis of master TFs CREB1 and FoxA1 in androgen-dependent prostate cancer (ADPC)...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Sunkel, Benjamin, Wu, Dayong, Chen, Zhong, Wang, Chiou-Miin, Liu, Xiangtao, Ye, Zhenqing, Horning, Aaron M., Liu, Joseph, Mahalingam, Devalingam, Lopez-Nicora, Horacio, Lin, Chun-Lin, Goodfellow, Paul J., Clinton, Steven K., Jin, Victor X., Chen, Chun-Liang, Huang, Tim H.-M., Wang, Qianben
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872073/
https://ncbi.nlm.nih.gov/pubmed/26743006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1528
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