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Genome-wide analysis reveals positional-nucleosome-oriented binding pattern of pioneer factor FOXA1
The compaction of nucleosomal structures creates a barrier for DNA-binding transcription factors (TFs) to access their cognate cis-regulatory elements. Pioneer factors (PFs) such as FOXA1 are able to directly access these cis-targets within compact chromatin. However, how these PFs interplay with nu...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027512/ https://ncbi.nlm.nih.gov/pubmed/27458208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw659 |
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