DNA helical stability accounts for mutational defects in a yeast replication origin.

Earlier studies on the H4 autonomously replicating sequence (ARS) identified a DNA unwinding element (DUE), a required sequence that is hypersensitive to single-strand-specific nucleases and serves to facilitate origin unwinding. Here we demonstrate that a DUE can be identified in the C2G1 ARS, a ch...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Natale, D A, Schubert, A E, Kowalski, D
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1992
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48720/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2654
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