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DNA helical stability accounts for mutational defects in a yeast replication origin.
Earlier studies on the H4 autonomously replicating sequence (ARS) identified a DNA unwinding element (DUE), a required sequence that is hypersensitive to single-strand-specific nucleases and serves to facilitate origin unwinding. Here we demonstrate that a DUE can be identified in the C2G1 ARS, a ch...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1992
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC48720/ https://ncbi.nlm.nih.gov/pubmed/1557369 |
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