DNA helical stability accounts for mutational defects in a yeast replication origin.
Earlier studies on the H4 autonomously replicating sequence (ARS) identified a DNA unwinding element (DUE), a required sequence that is hypersensitive to single-strand-specific nucleases and serves to facilitate origin unwinding. Here we demonstrate that a DUE can be identified in the C2G1 ARS, a ch...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48720/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2654 |
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