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Leishmania-encoded orthologs of macrophage migration inhibitory factor regulate host immunity to promote parasite persistence
Leishmania major encodes 2 orthologs of the cytokine macrophage migration inhibitory factor (MIF), whose functions in parasite growth or in the host–parasite interaction are unknown. To determine the importance of Leishmania-encoded MIF, both LmMIF genes were removed to produce an mif(−/−) strain of...
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| Publicat a: | FASEB J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Federation of American Societies for Experimental Biology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871794/ https://ncbi.nlm.nih.gov/pubmed/26956417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500189R |
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