Mass spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: Comparison to IHC and FISH

BACKGROUND: Trastuzumab showed survival benefit for Her2-positive gastroesophageal cancers (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, these low-throughput assays often produce discordant or e...

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Udgivet i:Gastric Cancer
Main Authors: Catenacci, Daniel V.T., Liao, Wei-Li, Zhao, Lei, Whitcomb, Emma, Henderson, Les, O’Day, Emily, Xu, Peng, Thyparambil, Sheeno, Krizman, David, Bengali, Kathleen, Uzzell, Jamar, Darfler, Marlene, Cecchi, Fabiola, Blackler, Adele, Bang, Yung-Jue, Hart, John, Xiao, Shu-Yuan, Lee, Sang Mee, Burrows, Jon, Hembrough, Todd
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871781/
https://ncbi.nlm.nih.gov/pubmed/26581548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10120-015-0566-0
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