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Paradoxical Effect of Non-Physiological Shear Stress on Platelets and von Willebrand factor

Blood can become hypercoagulable by shear-induced platelet activation and generation of microparticles. It has been reported that non-physiological shear stress (NPSS) could induce shedding of platelet receptor glycoprotein (GP) Ibα, which may result in an opposite effect to hemostasis. The aim of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Artif Organs
Hauptverfasser: Chen, Zengsheng, Mondal, Nandan K, Ding, Jun, Koenig, Steven C., Slaughter, Mark S., Wu, Zhongjun J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871771/
https://ncbi.nlm.nih.gov/pubmed/26582038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aor.12606
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