Mutant characterization and in vivo conditional repression identify aromatic amino acid biosynthesis to be essential for Aspergillus fumigatus virulence

Pathogenicity of the saprobe Aspergillus fumigatus strictly depends on nutrient acquisition during infection, as fungal growth determines colonisation and invasion of a susceptible host. Primary metabolism has to be considered as a valid target for antimycotic therapy, based on the fact that several...

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Detalles Bibliográficos
Publicado en:Virulence
Main Authors: Sasse, Anna, Hamer, Stefanie N, Amich, Jorge, Binder, Jasmin, Krappmann, Sven
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
Assuntos:
Brief Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871646/
https://ncbi.nlm.nih.gov/pubmed/26605426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2015.1109766
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