Mutant characterization and in vivo conditional repression identify aromatic amino acid biosynthesis to be essential for Aspergillus fumigatus virulence

Pathogenicity of the saprobe Aspergillus fumigatus strictly depends on nutrient acquisition during infection, as fungal growth determines colonisation and invasion of a susceptible host. Primary metabolism has to be considered as a valid target for antimycotic therapy, based on the fact that several...

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Bibliographische Detailangaben
Veröffentlicht in:Virulence
Hauptverfasser: Sasse, Anna, Hamer, Stefanie N, Amich, Jorge, Binder, Jasmin, Krappmann, Sven
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871646/
https://ncbi.nlm.nih.gov/pubmed/26605426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2015.1109766
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