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A novel toxicity scoring system treating toxicity response as a quasi-continuous variable in Phase I clinical trials
In almost all current Phase I designs, toxicity response is treated coarsely as a binary indicator of dose limiting toxicity (DLT) and a lot of useful toxicity information is discarded. We are the first to establish a novel toxicity scoring system to treat toxicity response as a quasi-continuous var...
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| Publicado no: | Contemp Clin Trials |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871599/ https://ncbi.nlm.nih.gov/pubmed/20609419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2010.05.010 |
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