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Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression

Cysteine peptidases play a central role in the biology of Leishmania. In this work, we sought to further elucidate the mechanism(s) by which the cysteine peptidase CPB contributes to L. mexicana virulence and whether CPB participates in the formation of large communal parasitophorous vacuoles induce...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Casgrain, Pierre-André, Martel, Caroline, McMaster, W. Robert, Mottram, Jeremy C., Olivier, Martin, Descoteaux, Albert
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871588/
https://ncbi.nlm.nih.gov/pubmed/27191844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005658
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