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Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression

Cysteine peptidases play a central role in the biology of Leishmania. In this work, we sought to further elucidate the mechanism(s) by which the cysteine peptidase CPB contributes to L. mexicana virulence and whether CPB participates in the formation of large communal parasitophorous vacuoles induce...

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Vydáno v:PLoS Pathog
Hlavní autoři: Casgrain, Pierre-André, Martel, Caroline, McMaster, W. Robert, Mottram, Jeremy C., Olivier, Martin, Descoteaux, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871588/
https://ncbi.nlm.nih.gov/pubmed/27191844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005658
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