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Both Complexity and Location of DNA Damage Contribute to Cellular Senescence Induced by Ionizing Radiation

Persistent DNA damage is considered as a main cause of cellular senescence induced by ionizing radiation. However, the molecular bases of the DNA damage and their contribution to cellular senescence are not completely clear. In this study, we found that both heavy ions and X-rays induced senescence...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Zhang, Xurui, Ye, Caiyong, Sun, Fang, Wei, Wenjun, Hu, Burong, Wang, Jufang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871470/
https://ncbi.nlm.nih.gov/pubmed/27187621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155725
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