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Both Complexity and Location of DNA Damage Contribute to Cellular Senescence Induced by Ionizing Radiation

Persistent DNA damage is considered as a main cause of cellular senescence induced by ionizing radiation. However, the molecular bases of the DNA damage and their contribution to cellular senescence are not completely clear. In this study, we found that both heavy ions and X-rays induced senescence...

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Publicat a:PLoS One
Autors principals: Zhang, Xurui, Ye, Caiyong, Sun, Fang, Wei, Wenjun, Hu, Burong, Wang, Jufang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871470/
https://ncbi.nlm.nih.gov/pubmed/27187621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155725
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